The Medical Protocol of Egg Donation Surrogacy: From Ovarian Stimulation to Embryo Transfer
2025-11-24 25 Admin

The 4 Key Medical Steps in Egg Donation Surrogacy

Step 1: Controlled Ovarian Stimulation (COS)

Based on the donor's ovarian reserve (AMH/FSH), our specialists design a personalized protocol using Gonadotropins (FSH/LH injections) to stimulate the growth of multiple follicles. Regular ultrasound monitoring is conducted over 10-12 days to track follicular maturation.

Step 2: Oocyte Retrieval & ICSI

Once follicles are mature, Oocyte Retrieval is performed under sedation. In the lab, embryologists employ ICSI (Intracytoplasmic Sperm Injection), injecting a single selected sperm directly into the cytoplasm of a mature egg (MII oocyte). This ensures high fertilization rates, even with male factor infertility.

Step 3: Blastocyst Culture

Fertilized eggs are cultured for 5 to 6 days until they reach the Blastocyst stage. A blastocyst consists of differentiated cells (Inner Cell Mass and Trophectoderm) and possesses significantly higher implantation potential compared to Day-3 cleavage stage embryos.

Step 4: Endometrial Preparation & Transfer (FET)

Crucial for success. The surrogate undergoes hormonal preparation (Estrogen/Progesterone) to thicken the Endometrium (lining) to the optimal 8-12mm. We precisely identify the "Window of Implantation" (WOI) before performing the Frozen Embryo Transfer (FET), maximizing the chances of a clinical pregnancy.


FAQ: The Medical Process

Q: How are surrogates screened?

A: ANVINO enforces strict screening. Surrogates must pass infectious disease testing, psychological evaluation, and a thorough uterine exam (Hysteroscopy) to ensure they are physically and mentally capable of carrying a healthy pregnancy.

Q: What happens if the first transfer fails?

A: In our Guaranteed Package, we cover the cost of subsequent transfers. If a transfer fails, the doctor will adjust the medication protocol for the surrogate's next cycle to improve endometrial receptivity.

Q: Is ICSI better than standard IVF?

A: Yes. For surrogacy cycles, we use ICSI as the standard because it significantly improves fertilization rates, ensuring we have more embryos available for culture and screening.

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