Why PGT-A is Critical for Surrogacy Success? Understanding the Science of Euploid Embryos
2025-12-02 21 Admin

Why PGT-A Screening is the "Gold Standard" for Surrogacy?

In Assisted Reproductive Technology (ART), a "good-looking" embryo under the microscope does not guarantee a healthy pregnancy. Studies show that even in young donors, approximately 30%-40% of embryos may carry Chromosomal Abnormalities (Aneuploidy). Transferring these embryos often leads to implantation failure, chemical pregnancy, or spontaneous miscarriage.

What is PGT-A?

PGT-A (Preimplantation Genetic Testing for Aneuploidy), formerly known as PGS, goes beyond morphology. It involves a biopsy of the Trophectoderm cells (the future placenta) from a Day-5 or Day-6 Blastocyst to analyze all 23 pairs of chromosomes.

  • The Goal: Identify Euploid Embryos — embryos with the correct number of chromosomes (46).
  • The Risk Avoided: Discard Aneuploid Embryos — the leading cause of recurrent implantation failure (RIF) and early pregnancy loss.

ANVINO's Standard: In our Guaranteed Surrogacy Packages, PGT-A is a mandatory protocol. By transferring only genetically competent Euploid Blastocysts, we significantly increase the Live Birth Rate per transfer, ensuring a safer journey for both the surrogate and the baby.


FAQ: PGT-A & Genetic Testing

Q: Is PGT-A biopsy safe for the embryo?

A: Yes, it is considered very safe. The biopsy is performed at the Blastocyst stage (Day 5-6), removing only a few cells from the Trophectoderm (which becomes the placenta), leaving the Inner Cell Mass (which becomes the baby) untouched.

Q: Can PGT-A determine the gender?

A: Yes. PGT-A analyzes the sex chromosomes (XY or XX). In jurisdictions where it is legal (e.g., USA, Georgia), you can choose to transfer a male or female embryo based on your family balancing needs.

Q: Does PGT-A guarantee a baby?

A: While PGT-A significantly increases the success rate (up to 70-80% per transfer), no medical procedure is 100% guaranteed on its own. That is why ANVINO offers a "Guaranteed Success Package" which includes unlimited transfers until a live birth is achieved.

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