The Foundation of IVF: Controlled Ovarian Stimulation

In a natural cycle, a woman typically releases only one mature egg. To maximize IVF success rates, we use Controlled Ovarian Stimulation (COS) to recruit multiple follicles that would otherwise undergo atresia (natural death), allowing us to retrieve multiple mature eggs in a single cycle.

At ANVINO's partner clinics, our goal isn't just "more eggs," but "the optimal balance of quantity and quality," while strictly preventing Ovarian Hyperstimulation Syndrome (OHSS).

Phase 1: Protocol Start (Day 1-3)

Your specialist will design a personalized protocol (e.g., Antagonist, Long Protocol) based on your hormone levels (FSH, LH, E2), AMH, and Antral Follicle Count (AFC).
Typically, injections of Gonadotropins (e.g., Gonal-f, Menopur) begin on Day 2 or 3 of your menstrual cycle, after a baseline ultrasound confirms no cysts are present.

Phase 2: Monitoring & Adjustment (Day 4-10)

This phase requires precise medical management. You will typically undergo 3-4 monitoring visits:

• Tools: Transvaginal Ultrasound (to measure follicle size) + Blood Work (E2, LH, Progesterone).
• Dose Adjustment: The doctor adjusts medication dosage based on growth speed. If follicles grow too fast or Estrogen gets too high, the dose is lowered to ensure safety.
• The Antagonist: When the lead follicle reaches 12-14mm, an "Antagonist" injection (e.g., Cetrotide) is added to prevent premature ovulation.

Phase 3: The Trigger Shot

When the majority of follicles reach 18-20mm in diameter, the doctor will instruct you to take the "Trigger Shot" (HCG or Lupron).
This injection mimics the natural LH surge and triggers the final maturation of the eggs.
Crucial: Egg retrieval must occur exactly 34-36 hours after this shot. Timing must be precise to the minute.